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Probiotic preparation VSL#3 induces remission in children with mild to moderate acute ulcerative colitis: A pilot study

Hien Q. Huynh, Jennifer deBruyn, Leluo Guan, Hugo Diaz, Meiju Li, Safwat Girgis, Justine Turner, Richard Fedorak, Karen Madsen

Journal:

Inflammatory Bowel Diseases

Année:

2009

Langue:

english

Fichier:

PDF, 150 KB

english, 2009

VSL#3 Probiotic-Mixture Induces Remission in Patients with Active Ulcerative Colitis

Bibiloni, Rodrigo, Fedorak, Richard N., Tannock, Gerald W., Madsen, Karen L., Gionchetti, Paolo, Campieri, Massimo, De Simone, Claudio, Sartor, R. Balfour

Journal:

American Journal of Gastroenterology

Année:

2005

Langue:

english

Fichier:

PDF, 131 KB

english, 2005

Clinical Aspects of Trace Elements: Zinc in Human Nutrition - Assessment of Zinc Status

Pluhator, Michelle M, Thomson, Alan Br, Fedorak, Richard N

Journal:

Canadian journal of gastroenterology

Année:

1996

Fichier:

PDF, 1.18 MB

1996

Bacterial overgrowth and inflammation of small intestine after carboxymethylcellulose ingestion in genetically susceptible mice

Alexander Swidsinski, Victoria Ung, Beate C. Sydora, Vera Loening-Baucke, Yvonne Doerffel, Hans Verstraelen, Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2009

Langue:

english

Fichier:

PDF, 457 KB

english, 2009

Certolizumab pegol, a monthly subcutaneously administered Fc-free anti-TNFα, improves health-related quality of life in patients with moderate to severe Crohn’s disease

Paul Rutgeerts, Stefan Schreiber, Brian Feagan, Dorothy L. Keininger, Liz O’Neil, Richard N. Fedorak, CDP870 Crohn’s Disease Study Group

Journal:

International Journal of Colorectal Disease

Année:

2008

Langue:

english

Fichier:

PDF, 250 KB

english, 2008

Bones and Crohn's. Risk factors associated with low bone mineral density in patients with Crohn's disease

Jesse S. Siffledeen, Richard N. Fedorak, Kerry Siminoski, Ho Jen, Eric Vaudan, Neena Abraham, Hillary Seinhart, Gordon Greenberg

Journal:

Inflammatory Bowel Diseases

Année:

2004

Langue:

english

Fichier:

PDF, 102 KB

english, 2004

Probiotics and the management of inflammatory bowel disease

Richard N. Fedorak, Karen L. Madsen

Journal:

Inflammatory Bowel Diseases

Année:

2004

Langue:

english

Fichier:

PDF, 254 KB

english, 2004

Metabolomics and detection of colorectal cancer in humans: a systematic review

Wang, Haili, Tso, Victor K, Slupsky, Carolyn M, Fedorak, Richard N

Journal:

Future Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2010

T1233 Patients with Inflammatory Bowel Disease Exhibit Dysregulated Mucosal Epithelial and Immune Responses to Bacterial DNA

Bach, Phil, Diaz, Hugo, St. Arnaud, Kevin, Fedorak, Richard, Madsen, Karen

Journal:

Gastroenterology

Année:

2008

Langue:

english

Fichier:

PDF, 78 KB

english, 2008

The Epidemiology of Inflammatory Bowel Disease in Canada: A Population-Based Study

Bernstein, Charles N., Wajda, Andre, Svenson, Lawrence W., MacKenzie, Adrian, Koehoorn, Mieke, Jackson, Maureen, Fedorak, Richard, Israel, David, Blanchard, James F.

Journal:

American Journal of Gastroenterology

Année:

2006

Langue:

english

Fichier:

PDF, 297 KB

english, 2006

The Probiotic VSL#3 Has Anti-inflammatory Effects and Could Reduce Endoscopic Recurrence After Surgery for Crohn's Disease

Fedorak, Richard N., Feagan, Brian G., Hotte, Naomi, Leddin, Des, Dieleman, Levinus A., Petrunia, Denis M., Enns, Robert, Bitton, Alain, Chiba, Naoki, Paré, Pierre, Rostom, Alaa, Marshall, John, Depew

Journal:

Clinical Gastroenterology and Hepatology

Année:

2015

Langue:

english

Fichier:

PDF, 788 KB

english, 2015

Probiotics and prebiotics in gastrointestinal disorders

Fedorak, Richard N., Madsen, Karen L.

Journal:

Current Opinion in Gastroenterology

Année:

2004

Langue:

english

Fichier:

PDF, 485 KB

english, 2004

Verapamil alters eicosanoid synthesis and accelerates healing during experimental colitis in rats

Fedorak, Richard N., Empey, Lonnie R., Walker, Keith

Journal:

Gastroenterology

Année:

1992

Langue:

english

Fichier:

PDF, 1010 KB

english, 1992

Prebiotic Supplementation Following Ileocecal Resection in a Murine Model is Associated With a Loss of Microbial Diversity and Increased Inflammation

Laffin, Michael, Perry, Troy, Park, Heekuk, Hotte, Naomi, Fedorak, Richard N, Thiesen, Aducio, Dicken, Bryan, Madsen, Karen L

Journal:

Inflammatory Bowel Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 8.37 MB

english, 2017

A BACH2 Gene Variant Is Associated with Postoperative Recurrence of Crohn’s Disease

Laffin, Michael R., Fedorak, Richard N., Wine, Eytan, Dicken, Bryan, Madsen, Karen L.

Journal:

Journal of the American College of Surgeons

Année:

2018

Langue:

english

Fichier:

PDF, 1015 KB

english, 2018

Thiopurine Methyltransferase Enzyme Activity Determination before Treatment of Inflammatory Bowel Disease with Azathioprine: Effect on Cost and Adverse Events

Sayani, Farzana A, Prosser, Connie, Bailey, Robert J, Jacobs, Philip, Fedorak, Richard N

Journal:

Canadian journal of gastroenterology

Année:

2005

Fichier:

PDF, 1.25 MB

2005

Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Requirements

Pluhator, Michelle M, Thomson, Alan BR, Fedorak, Richard N

Journal:

Canadian journal of gastroenterology

Année:

1995

Fichier:

PDF, 1.18 MB

1995

Steady-state pharmacokinetics of corticosteroid delivery from glucuronide prodrugs in normal and colitic rats

Harold W. Nolen III, Richard N. Fedorak, David R. Friend

Journal:

Biopharmaceutics & Drug Disposition

Année:

1997

Langue:

english

Fichier:

PDF, 511 KB

english, 1997

Epithelial barrier disruption allows nondisease-causing bacteria to initiate and sustain IBD in the IL-10 gene-deficient mouse

Beate C. Sydora, Sarah M. MacFarlane, John W. Walker, Andrea L. Dmytrash, Thomas A. Churchill, Jason Doyle, Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 286 KB

english, 2007

Endpoints for clinical trials evaluating disease modification and structural damage in adults with Crohn's disease

Geert R. D'Haens, Richard Fedorak, Marc Lémann, Brian G. Feagan, Michael A. Kamm, Jacques Cosnes, Paul J. Rutgeerts, Philippe Marteau, Simon Travis, Jürgen Schölmerich, Steven Hanauer, William J. Sand

Journal:

Inflammatory Bowel Diseases

Année:

2009

Langue:

english

Fichier:

PDF, 91 KB

english, 2009

Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohn's disease

Bruce E. Sands, Eric W. Jacobson, Thomas Sylwestrowicz, Ziad Younes, Gerald Dryden, Richard Fedorak, Susan Greenbloom

Journal:

Inflammatory Bowel Diseases

Année:

2010

Langue:

english

Fichier:

PDF, 349 KB

english, 2010

Neonatal exposure to fecal antigens reduces intestinal inflammation

Beate C. Sydora, Sarah M. McFarlane, Jason S. G. Doyle, Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2011

Langue:

english

Fichier:

PDF, 368 KB

english, 2011

Inadequate knowledge of immunization guidelines: A missed opportunity for preventing infection in immunocompromised IBD patients

James H. Yeung, Karen J. Goodman, Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2012

Langue:

english

Fichier:

PDF, 199 KB

english, 2012

Interleukin-10 gene-deficient mice develop a primary intestinal permeability defect in response to enteric microflora

Karen L. Madsen, David Malfair, Derek Gray, Jason S. Doyle, Laurence D. Jewell, Dr. Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

1999

Langue:

english

Fichier:

PDF, 1012 KB

english, 1999

Vanadate reduces sodium-dependent glucose transport and increases glycolytic activity in LLC-PK1 epithelia

Karen L. Madsen, Valerie M. Porter, Richard N. Fedorak

Journal:

Journal of Cellular Physiology

Année:

1994

Langue:

english

Fichier:

PDF, 1.00 MB

english, 1994

Nutritional and intestinal effects of the novel immunosuppressive agents: Deoxyspergualin, rapamycin, and mycophenolate mofetil

Natalie L. Yanchar, Richard N. Fedorak, Norman M. Kneteman, David L. Sigalet

Journal:

Clinical Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 785 KB

english, 1996

Is it time to re-classify Crohn's disease?

Richard N. Fedorak

Journal:

Best Practice & Research Clinical Gastroenterology

Année:

2004

Langue:

english

Fichier:

PDF, 84 KB

english, 2004

Acetic acid-induced colitis results in bystander ileal injury

Lonnie R. Empey, Ningren Cui, Richard N. Fedorak

Journal:

Inflammation Research

Année:

1993

Langue:

english

Fichier:

PDF, 822 KB

english, 1993

Association with Selected Bacteria Does Not Cause Enterocolitis in IL-10 Gene-Deficient Mice Despite a Systemic Immune Response

Beate C. Sydora, Michele M. Tavernini, Jason S. G. Doyle, Richard N. Fedorak

Journal:

Digestive Diseases and Sciences

Année:

2005

Langue:

english

Fichier:

PDF, 278 KB

english, 2005

CD4+CD25+Regulatory T Cells Have Divergent Effects on Intestinal Inflammation in IL-10 Gene-Deficient Mice

Beate C. Sydora, Sarah M. MacFarlane, Michele M. Tavernini, Jason S. G. Doyle, Richard N. Fedorak

Journal:

Digestive Diseases and Sciences

Année:

2008

Langue:

english

Fichier:

PDF, 331 KB

english, 2008

Oral Administration of Curcumin Emulsified in Carboxymethyl Cellulose Has a Potent Anti-inflammatory Effect in the IL-10 Gene-Deficient Mouse Model of IBD

Victoria Y. L. Ung, Rae R. Foshaug, Sarah M. MacFarlane, Thomas A. Churchill, Jason S. G. Doyle, Beate C. Sydora, Richard N. Fedorak

Journal:

Digestive Diseases and Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 261 KB

english, 2010

Naturally Occurring Glycoalkaloids in Potatoes Aggravate Intestinal Inflammation in Two Mouse Models of Inflammatory Bowel Disease

Vadim Iablokov, Beate C. Sydora, Rae Foshaug, Jon Meddings, Darcy Driedger, Tom Churchill, Richard N. Fedorak

Journal:

Digestive Diseases and Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 330 KB

english, 2010

Intravenous Injection of Endogenous Microbial Components Abrogates DSS-Induced Colitis

Beate C. Sydora, Eric J. Albert, Rae R. Foshaug, Jason S. G. Doyle, Thomas A. Churchill, Richard N. Fedorak

Journal:

Digestive Diseases and Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 440 KB

english, 2012

The role of antibiotic and probiotic therapies in current and future management of inflammatory Bowel disease

Julia B. Ewaschuk, Qassim Z. Tejpar, Isaac Soo, Karen L. Madsen, Richard N. Fedorak

Journal:

Current Gastroenterology Reports

Année:

2006

Langue:

english

Fichier:

PDF, 171 KB

english, 2006

The role of probiotics in management of irritable bowel syndrome

Anna M. Borowiec, Richard N. Fedorak

Journal:

Current Gastroenterology Reports

Année:

2007

Langue:

english

Fichier:

PDF, 488 KB

english, 2007

Drug−disease interaction: Crohn's disease elevates verapamil plasma concentrations but reduces response to the drug proportional to disease activity

Forough Sanaee, John D. Clements, Alistair W. G. Waugh, Richard N. Fedorak, Richard Lewanczuk, Fakhreddin Jamali

Journal:

British Journal of Clinical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2011

Lack of interleukin-10 leads to intestinal inflammation, independent of the time at which luminal microbial colonization occurs

Beate C. Sydora, Michele M. Tavernini, Andreas Wessler, Lawrence D. Jewell, Dr. Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2003

Langue:

english

Fichier:

PDF, 274 KB

english, 2003

Potato glycoalkaloids adversely affect intestinal permeability and aggravate inflammatory bowel disease

Bijal Patel, Robert Schutte, Peter Sporns, Jason Doyle, Lawrence Jewel, Dr. Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2002

Langue:

english

Fichier:

PDF, 182 KB

english, 2002

Normal breast milk limits the development of colitis in IL-10–deficient mice

Dr. Karen L. Madsen, Richard N. Fedorak, Michele M. Tavernini, Jason S. Doyle

Journal:

Inflammatory Bowel Diseases

Année:

2002

Langue:

english

Fichier:

PDF, 146 KB

english, 2002

Bacterial antigens alone can influence intestinal barrier integrity, but live bacteria are required for initiation of intestinal inflammation and injury

Beate C. Sydora, Sarah M. Martin, Maryla Lupicki, Levinus A. Dieleman, Jason Doyle, John W. Walker, Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2006

Langue:

english

Fichier:

PDF, 374 KB

english, 2006

A defect in epithelial barrier integrity is not required for a systemic response to bacterial antigens or intestinal injury in T cell receptor-α gene-deficient mice

Beate C. Sydora, Michele M. Tavernini, Jason Doyle, Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2006

Langue:

english

Fichier:

PDF, 312 KB

english, 2006

Postoperative Crohn's disease

Robert M Penner, Karen L Madsen, Richard N Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2005

Langue:

english

Fichier:

PDF, 152 KB

english, 2005

Antigenic Mimicry Between Helicobacter pylori and Gastric Mucosa: Failure to Implicate Heat-Shock Protein Hsp60 Using Immunoelectron Microscopy

Diane E. Taylor, Richard N. Fedorak, Richard Sherburne

Journal:

Helicobacter

Année:

1999

Langue:

english

Fichier:

PDF, 565 KB

english, 1999

Are there differences in type, dosage, and method of administration for the systemic steroids in IBD treatment?

Christopher Teshima, Richard N. Fedorak

Journal:

Inflammatory Bowel Diseases

Année:

2008

Langue:

english

Fichier:

PDF, 58 KB

english, 2008

Antidiarrheal therapy

Richard N. Fedorak, Michael Field

Journal:

Digestive Diseases and Sciences

Année:

1987

Langue:

english

Fichier:

PDF, 1.10 MB

english, 1987

Mucosal protective effects of vitamin E and misoprostol during acute radiation-induced enteritis in rats

Lonnie R. Empey, Jamie D. Papp, Lawrence D. Jewell, Richard N. Fedorak

Journal:

Digestive Diseases and Sciences

Année:

1992

Langue:

english

Fichier:

PDF, 2.92 MB

english, 1992

Effect of somatostatin analog (SMS 201-995) onin vivointestinal fluid transport in rats

Richard N. Fedorak, Sherie L. Allen

Journal:

Digestive Diseases and Sciences

Année:

1989

Langue:

english

Fichier:

PDF, 561 KB

english, 1989

Increased permeability occurs in rat ileum following induction of pancolitis

Ningren Cui, Karen L. Madsen, David R. Friend, Bruce R. Stevenson, Richard N. Fedorak

Journal:

Digestive Diseases and Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 1.13 MB

english, 1996

Adenocarcinoma of the pancreas coexisting with pancreatic abscess

Ihor J. Fedorak, Richard A. Frinz, Herbert B. Greenlee

Journal:

Journal of Gastrointestinal Cancer

Année:

1992

Langue:

english

Fichier:

PDF, 443 KB

english, 1992

Targeted delivery, safety, and efficacy of oral enteric-coated formulations of budesonide

Richard N. Fedorak, Lana Bistritz

Journal:

Advanced Drug Delivery Reviews

Année:

2005

Langue:

english

Fichier:

PDF, 167 KB

english, 2005